Niclosamide is a White to light yellow powder, odorless and tasteless. The melting point is 225-230°C. It is insoluble in water, but soluble in hot ethanol, chloroform, cyclohexanone, ether and sodium hydroxide solution.
Specification
Item
Specifications
Appearance
White to light yellow powder
Assay
98%-101%
Identity
Positive
5-chlorosalicyclic acid
≤60 ppm
2-chloro-4-nitroaniline
≤100 ppm
Chlorides
≤500 ppm
Related substances
≤0.2%
Melting point
227℃-232℃
Sulphated ash
≤0.1%
Loss on drying
≤0.5%
Application
1. Niclosamide, also known as p-tert-butylbenzyl chloride, can be used as an intermediate in the production of acaricides. 2. Niclosamide is used in synthesis of antiallergic drugs Anqimin and chlorpheniramine. 3. Niclosamide is used in medicine, pesticides and spices. 4. Niclosamide is used in Antiallergic drugs Anqimin, chlorpheniramine intermediates.